Stating that the NHS reforms will cause irreparable damage to patient care, scrapping the bill has been suggested by the professional body representing GPs.
Declaring outright opposition to the plans, Prime Minister has been sent a letter by the members of the Royal College of General Practitioners.
This opposition has come even from GPs despite the government planning to put them as main beneficiaries of the controversial reforms which would hand them direct control over NHS services and budgets in their local area.
The College wants the bill to be scrapped and for this they have approached David Cameron who is being urged to talk to the Prime Minister.
Grave opposition regarding the bill has been seen among medical profession, with the British Medical Association, the Royal College of Nursing and the Royal College of Midwives and others and the heat of this has been felt by ministers many times in the recent past.
Yesterday, RCGP chairman Dr Clare Gerada, who represents 34,000 doctors in England said, "Health and Social Care Bill would `turn the National Health Service into thousands of different health services, all competing for the same patients, the same knee, the same brain, the same heart. Our concerns from 18 months ago had still not been addressed."