A research has been published in the Journal of Clinical Oncology, which states that men receiving chemotherapy, radiotherapy or a combination of the two for testicular cancer may be on the riskier side of suffering from cardiovascular disease.
Along with colleagues, Hege S. Haugnes, M. D., of the University of Tromso in Norway, carried out a follow-up study upon 990 men, who had been undergoing treatment for unilateral TC.
The total number of men was divided into groups, where one belonged to the surgery group, chemotherapy only and RT only.
The aim of the experiment was to conclude the presence of cardiovascular risk contributors and the occurrence of CVD.
The group of researchers found that all groups that were getting cytotoxic treatment mainly indulged in taking antihypertensive medication.
Almost 74 TC survivors were afflicted with atherosclerotic disease.
Under the age-adjusted evaluation, the researchers noticed higher risks for people with atherosclerotic disease after they took cytotoxic treatment in comparison to undergoing surgery.
Volunteers getting treatment with cisplatin, bleomycin, and etoposide had increased risk of suffering from coronary artery disease and the risk was 5-7 times higher.
"Treatment with infradiaphragmatic RT and/or cisplatin-based chemotherapy, particularly the BEP regimen, increases the long-term risk for CVD in survivors of TC", the authors wrote.
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